Okay, this has been bothering me for a well. Wolf's Rain...Has nothing at all to do with Werewolves. If you think I'm wrong, trust me, you're not too educated on Japanese culture, and maybe you should just stop watching anime all together. XD Granted, and give me some leeway here, I'm picking on a specific idiot I once knew.
So for those of you who believe Wolf's Rain is not good because it ignores Lycanthropic lore, then again you don't know anything about Japanese lore. They are Okami, not any version of western werewolf. From my understanding which may or not be a 100% accurate, because the nuances of Japanese folklore is complex, and seemingly backwards from a western perspective, Japanese lore does not have a distinct line between the magical being or god, spirit. Therefore they are both a wolf as in an animal and mystical creature. So if you haven't watched the series in a few years, or maybe you wrote it off because of western perspectives and understandings try watching the story again, and see if you can come to love the nature verses humanity theme. I know I do.